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    Diagnosing early-stage AMD with a dark adaptation device

    Measuring dark adaptation impairment useful in screening for early AMD



    The adaptometer in daily clinical practice

    The dark adaptometer has been validated in clinical studies involving more than 1,000 patients, with additional studies ongoing. The device is also being used by a number of pharmaceutical companies in the development of drugs for early AMD and is proving to be a valuable research tool.


    However, equally important is its use in daily clinical practice. Currently, in my practice, I use OCT and autofluorescence to diagnose AMD. To date, I have only used the AdaptDx in clinical studies; however, I feel the device will be useful in helping us to identify early AMD patients and individuals who have a high probability of going on to develop the disease.


    This will allow us to guide the patient in taking preventative lifestyle measures. The only limitation in identifying early AMD is that we do not yet have drugs that can prevent disease progression. While this may seem frustrating at first for clinicians and patients alike, we can use this information to justify appropriate lifestyle modifications, such as weight loss, smoking cessation, eye health supplements and increased consumption of leafy green vegetables.


    Once AMD is detected, the adaptometer can be used to monitor disease progression so that we can intervene before vision loss occurs. Additionally, if we can further demonstrate a role for vitamins and antioxidant therapy in the prevention of AMD, using DA impairment testing to identify patients who are likely to develop AMD will be very valuable.


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