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    Dye from açai fruit safe, effective for use during chromovitrectomy


    The safety and efficacy investigations included evaluations of the physical and pre-anesthesia evaluations, surgical procedures, ophthalmic examination including measurement of the Snellen best-corrected visual acuity (BCVA), and other evaluations, such as electroretinography (ERG), fundus photography, fluorescein angiography, and optical coherence tomography (OCT) at baseline and 7, 30, 90, and 180 days postoperatively. Sixteen patients completed the 180-day examination, and all 25 patients completed the evaluations at the previous time points.

    The 10 surgeons completed a questionnaire immediately after they completed the macular hole surgeries regarding the ability of the dye to adequately stain the membranes. The surgeons graded the dye on a scale of 0 to 10, indicating, respectively, no staining and tissue identification similar to triamcinolone for posterior hyaloid detachment or brilliant blue for ILM identification. The ability of the açai fruit dye to stain the membranes was compared with the experience of each surgeon who used triamcinolone and brilliant blue as part of their current practice.

    Dr. Maia demonstrated the staining ability of the dye intraocularly.

    “The purple dye is heavy and goes directly to the posterior pole and no flushing of the dye is necessary,” he said. “Importantly, the posterior hyaloid is easily observed when stained in purple, which facilitated its detachment and removal.’

    The ILM is restained by the dye and it is easily observed and peeled based on the purple stain, he said.

    He also pointed out that 360° of ILM peeling was performed around the macular hole and that the OCT showed residual ILM that was peeled.


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