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    Suprachoroidal corticosteroid shows visual, anatomic improvements in DME eyes

     

    No adverse events

    There were no serious ocular or systemic adverse events and no unexpected or new safety signals.

    “Suprachoroidal CLS-TA has already completed other phase I and phase II trials, and there are multiple ongoing studies in phase II and phase III,” Dr. Wykoff said.

    Discussing limitations of the study, Dr. Wykoff noted the small sample size and short duration of the HULK trial, along with the variable disease management received by patients in the previously treated arms and different treatment exposures for the 2 arms during the 6-month trial.

    Charles C. Wykoff, MD, PhD

    e. [email protected]

    This article is based on a presentation given by Dr. Wykoff at the 2017 Retina Subspecialty Day prior to the 2017 American Academy of Ophthalmology meeting. Dr. Wykoff is a consultant to and receives grant support from Clearside Biomedical and from other companies that market or are developing treatments for DME. The HULK trial was supported by a grant from Clearside Biomedical.

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