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    Ultra-widefield angiography: New window for retinovascular features


    Future metric needed

    He commented on the importance of identifying an objective, easy-to-follow measurement tool for treating diabetic retinopathy. In particular, as new therapies emerge for diabetic retinopathy, an objective and quantifiable metric for gauging treatment response and need for ongoing treatment may be required to facilitate physician decision-making.

    “Overall, intravitreal aflibercept resulted in significant improvements in visual acuity and macular edema in this cohort,” Dr. Ehlers explained. “Additional ultra-widefield quantitative parameters showed significant reductions in microaneurysms, especially in the posterior pole, and in leakage and ischemia seen on the ultra-widefield angiography images.

    “Quantitative segmentation presents a unique opportunity for potential endpoints and for understanding some of the changes that occur in patients,” he added. “ In addition, higher order assessment of these imaging features, including potential machine learning, may provide new imaging biomarkers to better characterize these common retinal vascular diseases.”

    Justis Ehlers, MD

    e. [email protected]

    This article was adapted from a presentation that Dr. Ehlers delivered at the 2017 American Society of Retina Specialists meeting. Dr. Ehlers is an investigator for Regeneron Pharmaceuticals, which provided a research grant to fund this study.


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