Ophthalmology

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Treatment for geographic atrophy lacks efficacy in Phase 2 studyIn a placebo-controlled, dose-finding, proof-of-concept study conducted in patients with geographic atrophy secondary to age-related macular degeneration, an anti-amyloid β monoclonal antibody (GSK933776, GlaxoSmithKline) was safe and well-tolerated, but did not meet primary or secondary efficacy endpoints.
TREX-AMD trial finds visual gains from treat-and-extend vs. monthlyTreat-and-extend approach for neovascular AMD leads to beneficial results in 2-year clinical trial.
In vivo confocal microscopy ineffective for Fusarium and Aspergillus differentiationIt’s very hard to tell the difference between Fusarium and Aspergillus species with in vivo confocal microscopy (IVCM) of fungal keratitis, researchers say.
Pearls for better diagnosis, treatment of red eyeOphthalmologists should consider various potential problems, including a number of systemic conditions and infections, when examining a rare or persistent red eye.
Irritation in a bottle: Glaucoma and OSDOSD is of significant concern in patients with glaucoma on multiple topical medications. Optimal treatment of this condition with minimizing the intensity as well as with additional pharmacologic treatments for OSD can improve visual acuity and compliance and result in better outcomes both medically and regarding patient satisfaction.
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Managing glaucoma with surgical procedures (plural)The advent of low-risk surgical options is moving glaucoma from a pharmaceutically managed disease to one controlled via a series of surgical procedures. The outcome appears to be highly beneficial for patients, says Robert J. Noecker, MD.
Neuroprotective drug may be possible NAION therapyNon-arteritic ischemic optic neuropathy can be difficult to treat. A new drug under investigation aims to prevent further loss of vision from the condition.
Toric IOL’s transitional conic design enhances tolerance to misalignmentA novel toric IOL features an aberration-free, transitional conic anterior optic surface shows pupil independence and improved tolerance to misalignment in bench testing and excellent clinical outcomes.