ASRS 2017

Exploring sirolimus as potential alternative therapy for persistent AMDAnti-vascular endothelial growth factor (VEGF) therapy is highly successful, but as Raj Maturi, MD, pointed out, also has some limitations.
SHRM characteristics impact visual acuity in wet AMDSubretinal hyperreflective material (SHRM) is a morphologic component seen on optical coherence tomography (OCT) images as hyperreflective material that is external to the retina and internal to the retinal pigment epithelium (RPE), said Jaya B. Kumar, MD.
Priming syringe before injection associated with lower frequency of silicone oil dropletsAnother adverse effect associated with the compounding process of bevacizumab (Avastin, Genentech)—i.e., the presence of silicone oil droplets in the vitreous cavity—has surfaced within the past year and seems to be related to the preloading of the drug in insulin syringes.
Persistence is key when promoting surgical innovationsA surgical innovation is defined as a quantum improvement in the treatment of a particular disease or group of diseases, and it usually is developed by an individual or a small group working together, said John Thompson, MD.
DNA-based analysis identifies risk factor for metastasis of uveal melanomaCarol. L. Shields, MD, highlighted the results of collaborative efforts among four Philadelphia institutions: Wills Eye Hospital, Thomas Jefferson Hospital, the Genetics Department of the University of Pennsylvania, and the Wistar Instituate. The findings were published in Ophthalmology (Shields et al. 2017; published online May 7, 2017).
Unmasking retinal structure, function in X-linked retinoschisis“There is a compelling need to explore gene therapy in the eye,” according to Paul A. Sieving, MD, PhD.
Dye from açai fruit safe, effective for use during chromovitrectomy
Dye from açai fruit safe, effective for use during chromovitrectomyA dye made from the açai fruit (Euterpe oleracea) is safe for use in human eyes and effective for identifying the posterior hyaloid and internal limiting membrane (ILM) during vitreoretinal surgery, according to phase I preliminary study results.
Paracentral retinotomy facilitates closure of large, resistant macular holeRecognition of this problem resulted in an innovative approach for closing persistent macular holes after the primary surgery has failed by creating a separate paracentral retinotomy in the nasal macula. Michael S. Tsipursky, MD, described the rationale for trying this treatment approach. “
Reduced risk of CNV after SDM laser retinal protective therapyThe dry form of age-related macular degeneration (AMD) is the most common type of the disease, but successful treatments have been elusive in patients, resulting in disease progress and visual loss.
New concepts about macular edema emerge from modern imaging studiesVolume-rendered optical coherence tomography (OCT) imaging allows new insight into retinal vascular flow and morphological changes in eyes with macular edema (ME), and the information obtained is the basis for new ideas about the pathogenesis of ME and therapeutic intervention, according to Richard F. Spaide, MD, Vitreous Retina Macula Consultants of New York.
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